Search result: Catalogue data in Autumn Semester 2017

Biology Bachelor Information
3. Year, 5. Semester
Block Courses
Registration for Block courses is mandatory. Please register under https://www.uzh.ch/zoolmed/ssl-dir/Blockkurse_UNIETH.php . Registration period: from 24.7.2017 to 6.8.2017.
Block Courses in 2nd Quarter of the Semester
From 12.10.2017 08:00 Uhr to 3.11.2017 17:00 hr
NumberTitleTypeECTSHoursLecturers
551-0345-00LMechanisms of Bacterial Pathogenesis Restricted registration - show details
Number of participants limited to 9.

The enrolment is done by the D-BIOL study administration.
W6 credits7PW.‑D. Hardt, M. Diard, B. Nguyen
AbstractResearch laboratory class in small groups. Research projects on current topics in cellular microbiology and bacterial pathogenesis are assigned to each student.
ObjectiveIntroduction to a current topic in cellular microbiology and/or molecular genetics of a bacterial pathogen. Experimental work in the research lab and introduction to the current lab techniques. Work with the current research literature in bacterial pathogenesis. Writing of a research protocol.
Requirement for obtaining the credit points: oral presentation of the research project and evaluation of the research protocol.
ContentResearch projects on the model pathogen Salmonella.
Lecture notesnone.
LiteratureLiterature will be selected with reference to the assigned research project.
551-0421-00LBiology and Ecology of Fungi in Forests Information Restricted registration - show details
Number of participants limited to 10.

The enrolment is done by the D-BIOL study administration.
W6 credits7GI. L. Brunner, S. H. Egli, D. H. Rigling
AbstractIntroduction of the biological and ecological basics of fungi in forests. Focusing on mycorrhizal, saprobic, and pathogenic fungi and their functional relevance in the forest ecosystems. To get to know current methodological research approaches on the basis of selected examples with practical works in forest and lab as well as excursions and lectures.
ObjectiveKnowledge of the fungi of forest and its ecological significance. Knowing of current methodological research approaches. Self-reliant and deepened activities of selected topics of fungi from forests.
ContentIntroduction of the biological and ecological basics of fungi in forests. Focusing on mycorrhizal, saprobic, and pathogenic fungi and their functional relevance in the forest ecosystems. To get to know current methodological research approaches on the basis of selected examples with practical works in forest and lab as well as excursions and lectures.
Lecture notesUnterlagen zum Kurs werden abgegeben.
LiteratureBreitenbach J, Kränzlin F. 1980-2005. Pilze der Schweiz, Bände 1-6.
Flammer R, Horak E. 2003. Giftpilze-Pilzgifte. Schwabe, Basel.
Flück M. 2006. Pilzführer Schweiz. Haupt, Bern.
Smith S.E, Read D.J. 1997. Mycorrhizal Symbiosis. Academic Press, 2nd ed.
Prerequisites / NoticeDer Blockkurs findet an der Eidg. Forschungsanstalt WSL in Birmensdorf statt. Der Wald vor der Haustüre des Institutes macht diesen Kurs besonders praxisnah.

Erreichbarkeit mit Tram 14 bis Triemli, danach PTT-Bus 220 oder 350 bis Birmensdorf Sternen/WSL, oder mit S9 bis Birmensdorf SBB und mit PTT-Bus eine Station in Richtung Zürich bis Birmensdorf Sternen/WSL.
551-0359-00LPlant Biochemistry Information Restricted registration - show details
Number of participants limited to 15.

The enrolment is done by the D-BIOL study administration.
W6 credits7GS. C. Zeeman, B. Pfister
AbstractIn this block course, students actively participate in ongoing research projects on plant metabolism and are tutored individually by doctoral students and postdocs. In a lecture series, the theoretical background of the projects and their interrelationship is provided. Finally, students discuss their projects and results during a poster session.
ObjectiveIn this block course, students actively participate in ongoing research projects on plant metabolism and are tutored individually by doctoral students and postdocs.
ContentParticipation in the following research projects will be possible: Photosynthetic metabolism; how is photo-assimilated carbon allocated to sustain plant growth? Chloroplast biology; how is chloroplast function integrated with that to the whole cell? Starch biosynthesis and degradation; how are complex, semi-crystalline starch granules made from simple sugars, and once made, how are they degraded again to release the stored carbohydrate? Regulation of metabolism through protein-protein interaction; how and why do proteins involved in starch metabolism interact with each other to form multi-subunit enzymes and multi-enzyme complexes? Sugar sensing; How does a plant know how much sugar it has, and how does this influence development.
Lecture notesNo script
LiteratureDescriptions of the possible projects including individual reading assignments will be handed out beforehand.
551-1513-00LCancer Cell Signaling: Mechanisms, Targets and Therapeutic Approaches Information Restricted registration - show details
Number of participants limited to 10.

The enrolment is done by the D-BIOL study administration.
W6 credits7GW. Krek, W. Kovacs
AbstractThis course will consider the pathogenetic landscape of cancer, explore how abnormalities of cellular informationmanagement cause cancer and demonstrate how the integrated application of modern omics technologies, mouse cancer models and human pathology provides a foundation for developing individualized cancer therapeutics. The course combines practical work with discussions and presentations.
ObjectiveInsights into and overview about the genetic alterations that underlie different cancer types, the complex cancer cell circuitries governing tumor development, modern approaches used in contemporary basic and translational cancer research and sophisticated strategies to control individual cancers and combat drug resistance.
551-1147-00LBioactive Natural Products from Bacteria Restricted registration - show details
Number of participants limited to 8.

The enrolment is done by the D-BIOL study administration.
W6 credits7GJ. Piel
AbstractLab course. In small groups projects of relevance to current research questions in the field of bacterial natural product biosynthesis are addressed.
ObjectiveIntroduction to relevant subjects of the secondary metabolism of bacteria. Training in practical work in a research laboratory. Scientific writing in form of a research report.
ContentResearch project on bacteria that produce bioactive natural products (e.g., Streptomycetes, Cyanobacteria, uncultivated bacteria). The techniques used will depend on the project, e.g. PCR, cloning, natural product analysis, precursor feeding studies, enzyme expression and analysis.
Lecture notesnone.
LiteratureWill be provided for each of the projects at the beginning of the course.
551-0351-00LMembrane Biology Information Restricted registration - show details
Number of participants limited to 21.

The enrolment is done by the D-BIOL study administration.
W6 credits7GV. Korkhov, Y. Barral, B. Kornmann, U. Kutay, A. Rodriguez-Villalon, G. Schertler
AbstractThe course will introduce the students to the key concepts in membrane biology and will allow them to be involved in laboratory projects related to that broad field. The course will consist of lectures, literature discussions, and practical laboratory work in small groups. Results of the practical projects will be presented during the poster session at the end of the course.
ObjectiveThe aim of the course is to expose the students to a wide range of modern research areas encompassed by the field of membrane biology.
ContentStudents will be engaged in research projects aimed at understanding the biological membranes at the molecular, organellar and cellular levels. Students will design and perform experiments, evaluate experimental results, analyze the current scientific literature and understand the relevance of their work in the context of the current state of the membrane biology field.
Lecture notesNo script
LiteratureThe recommended literature, including reviews and primary research articles, will be provided during the course
Prerequisites / NoticeThe course will be taught in English. All general lectures will be held at ETH Hoenggerberg; special lectures will be organized by individual participating groups. Students will be divided into small groups to carry out experiments at ETH or at the Paul Scherrer Institute. Travel to the Paul Scherrer Insitute will be organized by car rental or public transportation.
551-1201-00LComputational Methods in Genome and Sequence Analysis Restricted registration - show details
Number of participants limited to 5.

The enrolment is done by the D-BIOL study administration.
W6 credits7GA. Wutz
AbstractThis course aims to provide students with a comprehensive overview of computational methods for sequence analysis and assist with developing skills for application of computational approaches by experimental scientists in the life sciences.
ObjectiveMethods for analyzing animal genomes are increasingly becoming important for applications in human health and biotechnology suggesting that the experience will be useful to develop relevant expertise for a broad range of functions. Students will have the opportunity to advance their knowledge in programming by focusing on algorithms for genome and gene sequence analysis. A major goal of the course will be to lead the student to an independent and empowered attitude towards computational problems. For reaching this goal the students will work on an implementation of a solution for a set real-world problem in genome and sequence analysis under guided supervision.
Content•Understanding the information in biological sequences and quantifying similarity
•Introduction to algorithms for sequence comparison and searches
•Implementation of sequence comparisons and searches in Python
•Accessing data formats associated with genome sequence analysis tasks
•Understanding the anatomy of a real world sequence analysis project
•Applying tools for sequence alignment and estimating error rates
•Ability to implement a solution to a problem in sequence analysis using Python
•Accessing genome annotation and retrieving relevant information in Pandas
•Application of Genomic intervals and arrays for sequence analysis with HTSeq

The course will consist of a series of lectures, assignments for implementing elementary tasks in Python, project development and discussion workshops, and 3 and a half week of practical work implementing a Pythons script as a solution to a real world problem associated with sequence analysis. At the end of the course students will explain their solutions and demonstrate the functionality of their implementations, which will then be discussed and commented on by the group. It is expected that students will be able to apply the knowledge to improve on concrete problems.
Prerequisites / Notice- It is recommended to bring your own computer with a Python installation to the course
- simple computers can be provided
- Programming basics with Python
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