Search result: Catalogue data in Spring Semester 2019
Biology Bachelor  | ||||||
 2. Year, 4. Semester | ||||||
| Elective Blocks | ||||||
| Biodiversity | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|---|
| 551-1174-00L | Systems Biology | O | 4 credits | 2V + 2U | U. Sauer, K. M. Borgwardt, J. Stelling, N. Zamboni | |
| Abstract | The course teaches computational methods and first hands-on applications by starting from biological problems/phenomena that students in the 4th semester are somewhat familiar with. During the exercises, students will obtain first experience with programming their own analyses/models for data analysis/interpretation. | |||||
| Objective | We will teach little if any novel biological knowledge or analysis methods, but focus on training the ability of use existing knowledge (for example from enzyme kinetics, regulatory mechanisms or analytical methods) to understand biological problems that arise when considering molecular elements in their context and to translate some of these problems into a form that can be solved by computational methods. Specific goals are: - understand the limitations of intuitive reasoning - obtain a first overview of computational approaches in systems biology - train ability to translate biological problems into computational problems - solve practical problems by programming with MATLAB - make first experiences in computational interpretation of biological data - understand typical abstractions in modeling molecular systems | |||||
| Content | During the first 7 weeks, the will focus on mechanistic modeling. Starting from simple enzyme kinetics, we will move through the dynamics of small pathways that also include regulation and end with flux balance analysis of a medium size metabolic network. During the second 7 weeks, the focus will shift to the analysis of larger data sets, such as metabolomics and transcriptomics that are often generated in biology. Here we will go through multivariate statistical methods that include clustering and principal component analysis, ending with first methods to learn networks from data. | |||||
| Lecture notes | Kein Skript | |||||
| Literature | The course is not taught by a particular book, but two books are suggested for further reading: - Systems Biology (Klipp, Herwig, Kowald, Wierling und Lehrach) Wiley-VCH 2009 - A First Course in Systems Biology (Eberhardt O. Voight) Garland Science 2012 | |||||
| 376-0152-00L | Anatomy and Physiology II | O | 5 credits | 4V | M. Ristow, K. De Bock, M. Kopf, L. Slomianka, C. Spengler | |
| Abstract | Basic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope. | |||||
| Objective | Foundations of human anatomy and physiology and basics of clinical pathophysiology | |||||
| Content | Short overview of human anatomy, physiology and general pathology. 3rd semester: Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system. 4rd semester: Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth. | |||||
| Literature | Anatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer; oder Spornitz, "Anatomie und Physiologie, Lehrbuch und Atlas für Pflege-und Gesundheitsfachberufe", Springer Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen, Wissenschaftliche Verlagsgesellschaft, Stuttgart oder Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg | |||||
| Prerequisites / Notice | Der Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut. | |||||
| 701-0360-00L | Systematic Biology: Plants  | O | 5 credits | 2V + 3P | A. Leuchtmann | |
| Abstract | The lecture provides an overview of the diversity of ferns and seed-plants. The fundamentals of systematics are given considering morphological, phylogenetic and ecological aspects. Regarding plant species, emphasis is laid on the flora of Switzerland, but also examples of pharmaceutical relevance and crop plants will be included. | |||||
| Objective | Students know: - the fundamentals of plant systematics - the higher-level plant groups based on morphological and biological characteristics - selected families of flowering plants - selected species and their ecology, with special focus on the flora of Switzerland - examples of medicinal and crop plants - ecological factors of sites and the most important vegetation types of the lowlands. | |||||
| Content | Die Vorlesung gibt einen Überblick über Moose, Farne, Gymnospermen und Angiospermen. Ausgewählte Familien der Angiospermen werden ausführlich behandelt. Weitere Themen sind Grundlagen der Pflanzensystematik, Generationswechsel, phylogenetische Stammbäume, morphologische Begriffe, sowie Lebensweise und Ökologie der Pflanzen. Anhand ausgewählter Beispiele wird auf die Bedeutung der Pflanzen als Arznei-, Zeiger- und Nutzpflanzen eingegangen. Zudem wird eine Übersicht über Standorteigenschaften und Vegetation des Tieflandes in der Schweiz gegeben. Im praktischen Teil lernen die Studierenden Merkmale von Blütenpflanzen zu analysieren und üben das Bestimmen von Pflanzenarten. Auf Exkursionen werden Artkenntnisse vermittelt und ein Einblick gegeben in Flora und Vegetation ausgewählter Standorte im Schweizer Mittelland, wobei auch einheimische Arzneipflanzen berücksichtigt werden. | |||||
| Literature | Baltisberger et al., Systematische Botanik. Einheimische Farn- und Samenpflanzen. vdf Hochschulverlag AG an der ETH Zürich (4. Aufl. 2013) Hess et al., Bestimmunsschlüssel zur Flora der Schweiz. Springer, Basel (7. Aufl. 2015) Baltisberger, Conradin, Frey & Rudow, 2016: eBot6. Internetapplikation. Für Studierende frei zugänglich unter http://www.balti.ethz.ch/tiki-index.php?page=eBot6. | |||||
| Prerequisites / Notice | Für Studierende der Pharmazeutischen Wissenschaften Bsc obligatorisch, für Studierende Biologie Bsc und Umweltnaturwissenschaften Bsc mit Vertiefungen in Ökologie und Evolution (Biologie), Wald und Landschaft oder Umweltbiologie besonders empfohlen. | |||||
| 701-0264-01L | Supplementary Course Systematic Botany Prerequisite: successful participation in 701-0360-00L Systematic Biology: Plants. It is recommended to enroll for both lectures in the same semester. | E- | 1 credit | 2P | A. Leuchtmann | |
| Abstract | Botanical excursions to Lower Engiadina providing extended systematic-botanical knowledge | |||||
| Objective | Participants know characters of important plant families and are able to assign species accordingly. They have gained extended knowledge of plant species, particularly of those relevant for the exam, and have received insight into flora and vegetation of the Lower Engiadina valley. | |||||
| Content | Exkursion in der montanen Stufe bei Klosters am ersten Tag, zwei weitere Exkursionen im Unterengadin. Vertiefung der systematisch-taxonomischen Kenntnisse und Einblick in Flora und Vegetation eines zentralalpinen Trockentals. Gruppenarbeit mit ausgewählten, neuen Pflanzenarten. | |||||
| Literature | Baltisberger et al., Systematische Botanik. Einheimische Farn- und Samenpflanzen. vdf Hochschulverlag AG an der ETH Zürich (4. Aufl. 2013) Hess et al. 2015. Bestimmunsschlüssel zur Flora der Schweiz. 7. Aufl., Springer, Basel. | |||||
| Prerequisites / Notice | Der Kurs richtet sich an Studierende Biologie Bsc und Umweltnaturwissenschaften Bsc; auch Studierende Pharmazeutische Wissenschaften Bsc sind willkommen. Der Besuch von "701-0360-00L Systematische Biologie: Pflanzen" wird vorausgesetzt, da der Kurs darauf aufbaut. Diese Lehrveranstaltung ist auf maximal 50 Teilnehmende beschränkt. Schriftliche Anmeldungen erforderlich, die nach Reihenfolge des Eingangs berücksichtigt werden. Kosten für Verpflegung und Unterkunft in Mehrbettzimmern (2 Nächte) müssen von den Teilnehmern übernommen werden (Fr. 80.-). | |||||
| 701-0245-00L | Introduction to Evolutionary Biology | O | 2 credits | 2V | G. Velicer, S. Wielgoss | |
| Abstract | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. | |||||
| Objective | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. The topics covered range from different forms of selection, phylogenetic analysis, population genetics, life history theory, the evolution of sex, social evolution to human evolution. These topics are important for the understanding of a number of evolutionary problems in the basic and applied sciences. | |||||
| Content | Topics likely to be covered in this course include research methods in evolutionary biology, adaptation, evolution of sex, evolutionary transitions, human evolution, infectious disease evolution, life history evolution, macroevolution, mechanisms of evolution, phylogenetic analysis, population dynamics, population genetics, social evolution, speciation and types of selection. | |||||
| Literature | Textbook: Evolutionary Analysis Scott Freeman and Jon Herron 5th Edition, English. | |||||
| Prerequisites / Notice | The exam is based on lecture and textbook. | |||||
| Cellular and Molecular Biology | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 551-1174-00L | Systems Biology | O | 4 credits | 2V + 2U | U. Sauer, K. M. Borgwardt, J. Stelling, N. Zamboni | |
| Abstract | The course teaches computational methods and first hands-on applications by starting from biological problems/phenomena that students in the 4th semester are somewhat familiar with. During the exercises, students will obtain first experience with programming their own analyses/models for data analysis/interpretation. | |||||
| Objective | We will teach little if any novel biological knowledge or analysis methods, but focus on training the ability of use existing knowledge (for example from enzyme kinetics, regulatory mechanisms or analytical methods) to understand biological problems that arise when considering molecular elements in their context and to translate some of these problems into a form that can be solved by computational methods. Specific goals are: - understand the limitations of intuitive reasoning - obtain a first overview of computational approaches in systems biology - train ability to translate biological problems into computational problems - solve practical problems by programming with MATLAB - make first experiences in computational interpretation of biological data - understand typical abstractions in modeling molecular systems | |||||
| Content | During the first 7 weeks, the will focus on mechanistic modeling. Starting from simple enzyme kinetics, we will move through the dynamics of small pathways that also include regulation and end with flux balance analysis of a medium size metabolic network. During the second 7 weeks, the focus will shift to the analysis of larger data sets, such as metabolomics and transcriptomics that are often generated in biology. Here we will go through multivariate statistical methods that include clustering and principal component analysis, ending with first methods to learn networks from data. | |||||
| Lecture notes | Kein Skript | |||||
| Literature | The course is not taught by a particular book, but two books are suggested for further reading: - Systems Biology (Klipp, Herwig, Kowald, Wierling und Lehrach) Wiley-VCH 2009 - A First Course in Systems Biology (Eberhardt O. Voight) Garland Science 2012 | |||||
| 376-0152-00L | Anatomy and Physiology II | O | 5 credits | 4V | M. Ristow, K. De Bock, M. Kopf, L. Slomianka, C. Spengler | |
| Abstract | Basic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope. | |||||
| Objective | Foundations of human anatomy and physiology and basics of clinical pathophysiology | |||||
| Content | Short overview of human anatomy, physiology and general pathology. 3rd semester: Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system. 4rd semester: Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth. | |||||
| Literature | Anatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer; oder Spornitz, "Anatomie und Physiologie, Lehrbuch und Atlas für Pflege-und Gesundheitsfachberufe", Springer Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen, Wissenschaftliche Verlagsgesellschaft, Stuttgart oder Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg | |||||
| Prerequisites / Notice | Der Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut. | |||||
| 529-0430-00L | Practical Course Physical Chemistry (for Biol./Pharm.Sci.) | O | 3 credits | 4P | E. C. Meister | |
| Abstract | Practical introduction to important basic experimental methods in physical chemistry. Investigation of qualitative and quantitative relations between physico-chemical quantities of the systems under study. | |||||
| Objective | The students have to carry out selected experiments in physical chemistry using important measurement methods and devices. The measured data have to be processed, mostly with the aid of computers, and considering error propagation and statistics. Detailed laboratory reports have to be written to each experiment. | |||||
| Content | Basic physical chemistry experiments covering chemical thermodynamics and kinetics, electrochemistry, viscosity and optical spectroscopy. Computer simulation of physical-chemical phenomena. | |||||
| Lecture notes | Erich Meister, Grundpraktikum Physikalische Chemie: Theorie und Experimente, 2. Auflage, vdf Hochschul-Verlag an der ETH, Zürich, 2012. Supplementary material to experiments is available. | |||||
| 701-0245-00L | Introduction to Evolutionary Biology | O | 2 credits | 2V | G. Velicer, S. Wielgoss | |
| Abstract | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. | |||||
| Objective | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. The topics covered range from different forms of selection, phylogenetic analysis, population genetics, life history theory, the evolution of sex, social evolution to human evolution. These topics are important for the understanding of a number of evolutionary problems in the basic and applied sciences. | |||||
| Content | Topics likely to be covered in this course include research methods in evolutionary biology, adaptation, evolution of sex, evolutionary transitions, human evolution, infectious disease evolution, life history evolution, macroevolution, mechanisms of evolution, phylogenetic analysis, population dynamics, population genetics, social evolution, speciation and types of selection. | |||||
| Literature | Textbook: Evolutionary Analysis Scott Freeman and Jon Herron 5th Edition, English. | |||||
| Prerequisites / Notice | The exam is based on lecture and textbook. | |||||
| Biological Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 551-1174-00L | Systems Biology | W | 4 credits | 2V + 2U | U. Sauer, K. M. Borgwardt, J. Stelling, N. Zamboni | |
| Abstract | The course teaches computational methods and first hands-on applications by starting from biological problems/phenomena that students in the 4th semester are somewhat familiar with. During the exercises, students will obtain first experience with programming their own analyses/models for data analysis/interpretation. | |||||
| Objective | We will teach little if any novel biological knowledge or analysis methods, but focus on training the ability of use existing knowledge (for example from enzyme kinetics, regulatory mechanisms or analytical methods) to understand biological problems that arise when considering molecular elements in their context and to translate some of these problems into a form that can be solved by computational methods. Specific goals are: - understand the limitations of intuitive reasoning - obtain a first overview of computational approaches in systems biology - train ability to translate biological problems into computational problems - solve practical problems by programming with MATLAB - make first experiences in computational interpretation of biological data - understand typical abstractions in modeling molecular systems | |||||
| Content | During the first 7 weeks, the will focus on mechanistic modeling. Starting from simple enzyme kinetics, we will move through the dynamics of small pathways that also include regulation and end with flux balance analysis of a medium size metabolic network. During the second 7 weeks, the focus will shift to the analysis of larger data sets, such as metabolomics and transcriptomics that are often generated in biology. Here we will go through multivariate statistical methods that include clustering and principal component analysis, ending with first methods to learn networks from data. | |||||
| Lecture notes | Kein Skript | |||||
| Literature | The course is not taught by a particular book, but two books are suggested for further reading: - Systems Biology (Klipp, Herwig, Kowald, Wierling und Lehrach) Wiley-VCH 2009 - A First Course in Systems Biology (Eberhardt O. Voight) Garland Science 2012 | |||||
| 529-0222-00L | Organic Chemistry II | O | 3 credits | 2V + 1U | J. W. Bode, B. Morandi | |
| Abstract | This course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. These topics are combined to the planning and execution of multiple step syntheses of complex molecules. | |||||
| Objective | Goals of this course include the a deeper understanding of basic organic reactions and mechanism as well as advanced and catalytic transformations (for example, Mitsunobu reactions, Corey-Chaykovsky epoxidation, Stetter reactions, etc). Reactive intermediates including carbenes and nitrenes are covered, along with methods for their generation and use in complex molecule synthesis. Frontier molecular orbital theory (FMO) is introduced and used to rationalize pericyclic reactions including Diels Alder reactions, cycloadditions, and rearrangements (Cope, Claisen). The basic concepts and key reactions of catalytic organometallic chemistry, which are key methods in modern organic synthesis, and introduced, with an emphasis on their catalytic cycles and elementrary steps. All of these topics are combined in an overview of strategies for complex molecule synthesis, with specific examples from natural product derived molecules used as medicines. | |||||
| Content | Oxidation and reduction of organic compounds, redox netural reactions and rearrangments, advanced transformations of functional groups and reaction mechanismes, kinetic and thermodynamic control of organic reactions, carbenes and nitrenes, frontier molecular orbital theory (FMO), cycloadditions and pericyclic reactions, introduction to organometallic chemistry and catalytic cross couplings, introduction to peptide synthesis and protecting groups, retrosynthetic analysis of complex organic molecules, planning and execution of multi-step reaction. | |||||
| Lecture notes | The lecture notes and additional documents including problem sets are available as PDF files online, without charge. Link: http://www.bode.ethz.ch/education.html | |||||
| Literature | Clayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012. | |||||
| 529-0430-00L | Practical Course Physical Chemistry (for Biol./Pharm.Sci.) | O | 3 credits | 4P | E. C. Meister | |
| Abstract | Practical introduction to important basic experimental methods in physical chemistry. Investigation of qualitative and quantitative relations between physico-chemical quantities of the systems under study. | |||||
| Objective | The students have to carry out selected experiments in physical chemistry using important measurement methods and devices. The measured data have to be processed, mostly with the aid of computers, and considering error propagation and statistics. Detailed laboratory reports have to be written to each experiment. | |||||
| Content | Basic physical chemistry experiments covering chemical thermodynamics and kinetics, electrochemistry, viscosity and optical spectroscopy. Computer simulation of physical-chemical phenomena. | |||||
| Lecture notes | Erich Meister, Grundpraktikum Physikalische Chemie: Theorie und Experimente, 2. Auflage, vdf Hochschul-Verlag an der ETH, Zürich, 2012. Supplementary material to experiments is available. | |||||
| 376-0152-00L | Anatomy and Physiology II | W | 5 credits | 4V | M. Ristow, K. De Bock, M. Kopf, L. Slomianka, C. Spengler | |
| Abstract | Basic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope. | |||||
| Objective | Foundations of human anatomy and physiology and basics of clinical pathophysiology | |||||
| Content | Short overview of human anatomy, physiology and general pathology. 3rd semester: Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system. 4rd semester: Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth. | |||||
| Literature | Anatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer; oder Spornitz, "Anatomie und Physiologie, Lehrbuch und Atlas für Pflege-und Gesundheitsfachberufe", Springer Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen, Wissenschaftliche Verlagsgesellschaft, Stuttgart oder Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg | |||||
| Prerequisites / Notice | Der Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut. | |||||
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