Suchergebnis: Katalogdaten im Herbstsemester 2016

Gesundheitswissenschaften und Technologie Master Information
Vertiefung in Neurowissenschaften
Pflichtfächer
NummerTitelTypECTSUmfangDozierende
376-0300-00LTranslational Science for Health and Medicine Belegung eingeschränkt - Details anzeigen O3 KP2GJ. Goldhahn, C. Wolfrum
KurzbeschreibungTranslational science is a cross disciplinary scientific research that is motivated by the need for practical applications that help people. The course should help to clarify basics of translational science, illustrate successful applications and should enable students to integrate key features into their future projects.
LernzielAfter completing this course, students will be able to understand:
Principles of translational science (including project planning, ethics application, basics of resource management and interdisciplinary communication)
InhaltWhat is translational science and what is it not?
How to identify need?
- Disease concepts and consequences for research
- Basics about incidence, prevalence etc., and orphan indications
How to choose the appropriate research type and methodology
- Ethical considerations including ethics application
- Pros and cons of different types of research
- Coordination of complex approaches incl. timing and resources
How to measure success?
- Outcome variables
- Improving the translational process
Challenges of communication?
How independent is translational science?
- Academic boundary conditions vs. industrial influences
Positive and negative examples will be illustrated by distinguished guest speakers.
Wahlfächer
Wahlfächer I
NummerTitelTypECTSUmfangDozierende
376-1305-00LDevelopment of the Nervous SystemW3 KP2VE. Stoeckli, weitere Dozierende
KurzbeschreibungDer Kurs behandelt die Entwicklung des Nervensystems (NS) mit Schwergewicht auf Neurogenese und Migration, Axonwachstum, Synapsenbildung, mol. & zell. Mechanismen und Krankheiten des sich entwickelnden NS.
LernzielZiel ist, einen vertieften Einblick in die normale Entwicklung des Nervensystems zu verschaffen auf Grund molekularer, zellulärer und biochemischer Ansätze.
InhaltDas Hauptmerk liegt auf der Entwicklung des NS: Frühentwicklung des Nervensystems, zelluläre Prozesse, Nervenfaserwachstum, Bildung von Synapsen und neuronaler Schaltkreise.
SkriptMuss vom OLAT runtergeladen werden: https://www.olat.uzh.ch/olat/dmz/
unter BIO344
LiteraturDiese Vorlesung setzt das Lesen von Buchkapiteln, Handouts und Originalliteratur voraus. Weitere Informationen dazu werden in den verschiedenen Vorlesungsstunden abgegeben bzw. sind im OLAT vermerkt.
Voraussetzungen / BesonderesPrüfung 9. Januar 2017, 9h-10.30h Irchel Y24-G-45
Repetition 28. Februar 2017, 16h-17.30h Irchel Y03-G-85
376-1305-01LStructure, Plasticity and Repair of the Nervous System Information W3 KP2VM. E. Schwab, L. Filli, K. A. Martin, weitere Dozierende
KurzbeschreibungDer Kurs behandelt die Struktur, Plastizität und Regeneration des adulten Nervensystems (NS) mit Schwerpunkt auf: sensorische Systeme, kognitive Funktionen, Lernen und Gedächtnis, molekulare und zelluläre Mechanismen, Tiermodelle und Krankheiten des NS.
LernzielBasierend auf molekularen, zellulären und biochemischen Ansätzen soll ein vertiefter Einblick in die Struktur, Plastizität und Regeneration des Nervensystems verschafft werden.
InhaltDas Hauptmerk liegt auf der Struktur, Plastizität und Regeneration des NS: Biologie des erwachsenen Nervensystems, Strukturelle Plastizität des adulten Nervensystems, Regeneration und Reparatur, Netzwerke und Nervenfasern, Regeneration, pathologischer Zellverlust.
SkriptETH-Studenten: Skript wird auf Moodle zur Verfügung gestellt https://moodle-app2.let.ethz.ch/course/view.php?id=694
Einschreibeschlüssel wird zu Beginn der Vorlesung zur Verfügung gestellt.

UZH-Studenten: Skript wird auf OLAT zur Verfügung gestellt https://www.olat.uzh.ch/olat/dmz/
LiteraturDiese Vorlesung setzt das Lesen von Buchkapiteln, Handouts und Originalliteratur voraus. Weitere Informationen dazu werden in den verschiedenen Vorlesungsstunden abgegeben bzw. sind im Moodle / OLAT vermerkt.
551-0309-00LConcepts in Modern GeneticsW6 KP4VY. Barral, D. Bopp, A. Hajnal, M. Stoffel, O. Voinnet
KurzbeschreibungConcepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference.
LernzielThis course focuses on the concepts of classical and modern genetics and genomics.
InhaltThe topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference.
SkriptScripts and additional material will be provided during the semester.
Voraussetzungen / BesonderesThis course is a co-production of the University of Zurich and ETH Zurich, and will be taught in English. The course takes place on Monday afternoon at ETH Hoenggerberg, and on Tuesday morning at UZH Irchel.
Wahlfächer II
NummerTitelTypECTSUmfangDozierende
151-0104-00LUncertainty Quantification for Engineering & Life Sciences Belegung eingeschränkt - Details anzeigen
Findet dieses Semester nicht statt.
Number of participants limited to 60.
W4 KP3GP. Koumoutsakos
KurzbeschreibungQuantification of uncertainties in computational models pertaining to applications in engineering and life sciences. Exploitation of massively available data to develop computational models with quantifiable predictive capabilities. Applications of Uncertainty Quantification and Propagation to problems in mechanics, control, systems and cell biology.
LernzielThe course will teach fundamental concept of Uncertainty Quantification and Propagation (UQ+P) for computational models of systems in Engineering and Life Sciences. Emphasis will be placed on practical and computational aspects of UQ+P including the implementation of relevant algorithms in multicore architectures.
InhaltTopics that will be covered include: Uncertainty quantification under
parametric and non-parametric modelling uncertainty, Bayesian inference with model class assessment, Markov Chain Monte Carlo simulation, prior and posterior reliability analysis.
SkriptThe class will be largely based on the book: Data Analysis: A Bayesian Tutorial by Devinderjit Sivia as well as on class notes and related literature that will be distributed in class.
Literatur1. Data Analysis: A Bayesian Tutorial by Devinderjit Sivia
2. Probability Theory: The Logic of Science by E. T. Jaynes
3. Class Notes
Voraussetzungen / BesonderesFundamentals of Probability, Fundamentals of Computational Modeling
227-0447-00LImage Analysis and Computer Vision Information W6 KP3V + 1UL. Van Gool, O. Göksel, E. Konukoglu
KurzbeschreibungLight and perception. Digital image formation. Image enhancement and feature extraction. Unitary transformations. Color and texture. Image segmentation and deformable shape matching. Motion extraction and tracking. 3D data extraction. Invariant features. Specific object recognition and object class recognition.
LernzielOverview of the most important concepts of image formation, perception and analysis, and Computer Vision. Gaining own experience through practical computer and programming exercises.
InhaltThe first part of the course starts off from an overview of existing and emerging applications that need computer vision. It shows that the realm of image processing is no longer restricted to the factory floor, but is entering several fields of our daily life. First it is investigated how the parameters of the electromagnetic waves are related to our perception. Also the interaction of light with matter is considered. The most important hardware components of technical vision systems, such as cameras, optical devices and illumination sources are discussed. The course then turns to the steps that are necessary to arrive at the discrete images that serve as input to algorithms. The next part describes necessary preprocessing steps of image analysis, that enhance image quality and/or detect specific features. Linear and non-linear filters are introduced for that purpose. The course will continue by analyzing procedures allowing to extract additional types of basic information from multiple images, with motion and depth as two important examples. The estimation of image velocities (optical flow) will get due attention and methods for object tracking will be presented. Several techniques are discussed to extract three-dimensional information about objects and scenes. Finally, approaches for the recognition of specific objects as well as object classes will be discussed and analyzed.
SkriptCourse material Script, computer demonstrations, exercises and problem solutions
Voraussetzungen / BesonderesPrerequisites:
Basic concepts of mathematical analysis and linear algebra. The computer exercises are based on Linux and C.
The course language is English.
227-1037-00LIntroduction to Neuroinformatics Information W6 KP2V + 1UK. A. Martin, M. Cook, V. Mante, M. Pfeiffer
KurzbeschreibungThe course provides an introduction to the functional properties of neurons. Particularly the description of membrane electrical properties (action potentials, channels), neuronal anatomy, synaptic structures, and neuronal networks. Simple models of computation, learning, and behavior will be explained. Some artificial systems (robot, chip) are presented.
LernzielUnderstanding computation by neurons and neuronal circuits is one of the great challenges of science. Many different disciplines can contribute their tools and concepts to solving mysteries of neural computation. The goal of this introductory course is to introduce the monocultures of physics, maths, computer science, engineering, biology, psychology, and even philosophy and history, to discover the enchantments and challenges that we all face in taking on this major 21st century problem and how each discipline can contribute to discovering solutions.
InhaltThis course considers the structure and function of biological neural networks at different levels. The function of neural networks lies fundamentally in their wiring and in the electro-chemical properties of nerve cell membranes. Thus, the biological structure of the nerve cell needs to be understood if biologically-realistic models are to be constructed. These simpler models are used to estimate the electrical current flow through dendritic cables and explore how a more complex geometry of neurons influences this current flow. The active properties of nerves are studied to understand both sensory transduction and the generation and transmission of nerve impulses along axons. The concept of local neuronal circuits arises in the context of the rules governing the formation of nerve connections and topographic projections within the nervous system. Communication between neurons in the network can be thought of as information flow across synapses, which can be modified by experience. We need an understanding of the action of inhibitory and excitatory neurotransmitters and neuromodulators, so that the dynamics and logic of synapses can be interpreted. Finally, the neural architectures of feedforward and recurrent networks will be discussed in the context of co-ordination, control, and integration of sensory and motor information in neural networks.
227-1045-00LReadings in Neuroinformatics (University of Zurich) Belegung eingeschränkt - Details anzeigen
No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH.
UZH Module Code: INI431

Mind the enrolment deadlines at UZH:
http://www.uzh.ch/studies/application/mobilitaet_en.html
W3 KP1SG. Indiveri, M. Cook, D. Kiper
KurzbeschreibungThirteen major areas of research have been selected, which cover the key concepts that have led to our current ideas of how the nervous system is built and functions. We will read both original papers and explore the conceptual the links between them and discuss the 'sociology' of science, the pursuit of basic science questions over a century of research."
LernzielIt is a commonplace that scientists rarely cite literature that is older than 10 years and when they do, they usually cite one paper that serves as the representative for a larger body of work that has long since been incorporated anonymously in textbooks. Worse than that, many authors have not even read the papers they cite in their own publications. This course, ‘Foundations of Neuroscience’ is one antidote. Thirteen major areas of research have been selected, which cover the key concepts that have led to our current ideas of how the nervous system is built and functions. Unusually, we will explore these areas of research by reading the original publications, instead of reading someone else’s digested summary from a textbook or review. By doing this, we will learn how the discoveries were made, what instrumentation was used, how the scientists interpreted their own findings, and how their work, often over many decades and linked together with related findings from many different scientists, generate the current views of mechanism and structure of the nervous system. To give one concrete example, in 1890 Roy and Sherrington showed that there was a neural activity-dependent regulation of blood flow in the brain. One hundred years later, Ogawa discovered that they could use Nuclear Magnetic Resonance (NMR) to measure a blood oxygen-level dependent (BOLD) signal, which they showed was neural activity-dependent. This discovery led to the development of human functional Magnetic Resonance Imaging (fMRI), which has revolutionized neuropsychology and neuropsychiatry. We will read both these original papers and explore the conceptual the links between them and discuss the ‘sociology’ of science, which in this case, the pursuit of basic science questions over a century of research, led to an explosion in applications. We will also explore the personalities of the scientists and the context in which they made their seminal discoveries. Each week the course members will be given original papers to read for homework, they will have to write a short abstract for each paper. We will then meet weekly with the course leader (KACM) and an assistant for an hour-or-so long interactive seminar. An intimate knowledge of the papers will be assumed so that the discussion does not center simply on an explication of the contents of the papers. Assessment will in the form of a written exam in which the students will be given a paper and asked to write a short abstract of the contents.
InhaltIt is a commonplace that scientists rarely cite literature that is older than 10 years and when they do, they usually cite one paper that serves as the representative for a larger body of work that has long since been incorporated anonymously in textbooks. Worse than that many authors have not even read the papers they cite in their own publications. This course, ‘Foundations of Neuroscience’ is one antidote. Thirteen major areas of research have been selected, which cover the key concepts that have led to our current ideas of how the nervous system is built and functions. Unusually, we will explore these areas of research by reading the original publications, instead of reading someone else’s digested summary from a textbook or review. By doing this, we will learn how the discoveries were made, what instrumentation was used, how the scientists interpreted their own findings, and how their work, often over many decades and by many different scientists, linked together to generate the current view of mechanism and structure. We will also explore the personalities of the scientists and the context in which they made their seminal discoveries. To give one concrete example, in 1890 Roy and Sherrington showed that there was a neural activity-dependent regulation of blood flow in the brain. One hundred years later, Ogawa discovered that they could use Nuclear Magnetic Resonance (NMR) to measure a blood oxygen-level dependent (BOLD) signal, which they showed was neural activity-dependent. This discovery led to the development of human functional Magnetic Resonance Imaging (fMRI), which has revolutionized neuropsychology and neuropsychiatry. We will read both these original papers and explore the conceptual links between them and discuss the ‘sociology’ of science, which in this case, the pursuit of basic science questions over a century of research, led to an explosion in applications. Each week the course members will be given between 2 and 4 papers to read for homework and we will then meet weekly for an hour long interactive seminar. An intimate knowledge of the papers will be assumed so that the discussion does not center simply on an explication of the contents of the papers. Assessment will be done continuously as the individual students are asked to explain a figure, technique, or concept.
227-1047-00LConsciousness: From Philosophy to Neuroscience (University of Zurich) Information
No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH.
UZH Module Code: INI410

Mind the enrolment deadlines at UZH:
http://www.uzh.ch/studies/application/mobilitaet_en.html
W3 KP2VD. Kiper, A. Gamma
KurzbeschreibungThis seminar reviews the philosophical and phenomenological as well as the neurobiological aspects of consciousness. The subjective features of consciousness are explored, and modern research into its neural substrate, particularly in the visual domain, is explained. Emphasis is placed on students developing their own thinking through a discussion-centered course structure.
LernzielThe course's goal is to give an overview of the contemporary state of consciousness research, with emphasis on the contributions brought by modern cognitive neuroscience. We aim to clarify concepts, explain their philosophical and scientific backgrounds, and to present experimental protocols that shed light on on a variety of consciousness related issues.
InhaltThe course includes discussions of scientific as well as philosophical articles. We review current schools of thought, models of consciousness, and proposals for the neural correlate of consciousness (NCC).
SkriptNone
LiteraturWe display articles pertaining to the issues we cover in the class on the course's webpage.
Voraussetzungen / BesonderesSince we are all experts on consciousness, we expect active participation and discussions!
327-2125-00LMicroscopy Training SEM I - Introduction to SEM Belegung eingeschränkt - Details anzeigen
Number of participants limited to 6.
The participants will be chosen based on a short motivation letter. Please send this letter to S. Rodighiero (main lecturer) as soon as possible.
W1 KP3PS. Rodighiero, A. G. Bittermann, K. Kunze, J. Reuteler
KurzbeschreibungDer Einführungskurs in Rasterelektronenmikroskopie (SEM) betont praktisches Lernen. Die Studierenden haben die Möglichkeit an zwei Elektronenmikroskopen ihre eigenen Proben oder Standard-Testproben zu untersuchen, sowie von ScopeM-Wissenschafler vorbereitete Übungen zu lösen.
Lernziel- Set-up, align and operate a SEM successfully and safely.
- Accomplish imaging tasks successfully and optimize microscope performances.
- Master the operation of a low-vacuum and field-emission SEM and EDX instrument.
- Perform sample preparation with corresponding techniques and equipment for imaging and analysis
- Acquire techniques in obtaining secondary electron and backscatter electron micrographs
- Perform EDX qualitative and semi-quantitative analysis
InhaltDuring the course, students learn through lectures, demonstrations, and hands-on sessions how to setup and operate SEM instruments, including low-vacuum and low-voltage applications.
This course gives basic skills for students new to SEM. At the end of the course, students with no prior experience are able to align a SEM, to obtain secondary electron (SE) and backscatter electron (BSE) micrographs and to perform energy dispersive X-ray spectroscopy (EDX) qualitative and semi-quantitative analysis. The procedures to better utilize SEM to solve practical problems and to optimize SEM analysis for a wide range of materials will be emphasized.

- Discussion of students' sample/interest
- Introduction and discussion on Electron Microscopy and instrumentation
- Lectures on electron sources, electron lenses and probe formation
- Lectures on beam/specimen interaction, image formation, image contrast and imaging modes.
- Lectures on sample preparation techniques for EM
- Brief description and demonstration of the SEM microscope
- Practice on beam/specimen interaction, image formation, image contrast (and image processing)
- Student participation on sample preparation techniques
- Scanning Electron Microscopy lab exercises: setup and operate the instrument under various imaging modalities
- Lecture and demonstrations on X-ray micro-analysis (theory and detection), qualitative and semi-quantitative EDX and point analysis, linescans and spectral mapping
- Practice on real-world samples and report results
Literatur- Detailed course manual
- Williams, Carter: Transmission Electron Microscopy, Plenum Press, 1996
- Hawkes, Valdre: Biophysical Electron Microscopy, Academic Press, 1990
- Egerton: Physical Principles of Electron Microscopy: an introduction to TEM, SEM and AEM, Springer Verlag, 2007
Voraussetzungen / BesonderesNo mandatory prerequisites. Please consider the prior attendance to EM Basic lectures (551- 1618-00V; 227-0390-00L; 327-0703-00L) as suggested prerequisite.
327-2126-00LMicroscopy Training TEM I - Introduction to TEM Belegung eingeschränkt - Details anzeigen
Findet dieses Semester nicht statt.
Number of participants limited to 6.

The participants will be chosen based on a short motivation letter. Please send this letter to S. Rodighiero (main lecturer).
W1 KP3P
KurzbeschreibungDer Einführungskurs in Transmissionselektronenmikroskopie (TEM) bietet neuen Nutzern die Möglichkeit theoretisches Wissen und praktische Kenntnisse in TEM zu erwerben
Lernziel- Overview of TEM theory, instrumentation, operation and applications.
- Alignment and operation of a TEM, as well as acquisition and interpretation of images, diffraction patterns, accomplishing basic tasks successfully.
- Knowledge of electron imaging modes (including Scanning Transmission Electron Microscopy), magnification calibration, and image acquisition using CCD cameras.
- To set up the TEM to acquire diffraction patterns, perform camera length calibration, as well as measure and interpret diffraction patterns.
- Overview of techniques for specimen preparation.
InhaltUsing two Transmission Electron Microscopes the students learn how to align a TEM, select parameters for acquisition of images in bright field (BF) and dark field (DF), perform scanning transmission electron microscopy (STEM) imaging, phase contrast imaging, and acquire electron diffraction patterns. The participants will also learn basic and advanced use of digital cameras and digital imaging methods.

- Introduction and discussion on Electron Microscopy and instrumentation.
- Lectures on electron sources, electron lenses and probe formation.
- Lectures on beam/specimen interaction, image formation, image contrast and imaging modes.
- Lectures on sample preparation techniques for EM.
- Brief description and demonstration of the TEM microscope.
- Practice on beam/specimen interaction, image formation, Image contrast (and image processing).
- Demonstration of Transmission Electron Microscopes and imaging modes (Phase contrast, BF, DF, STEM).
- Student participation on sample preparation techniques.
- Transmission Electron Microscopy lab exercises: setup and operate the instrument under various imaging modalities.
- TEM alignment, calibration, correction to improve image contrast and quality.
- Electron diffraction.
- Practice on real-world samples and report results.
Literatur- Detailed course manual
- Williams, Carter: Transmission Electron Microscopy, Plenum Press, 1996
- Hawkes, Valdre: Biophysical Electron Microscopy, Academic Press, 1990
- Egerton: Physical Principles of Electron Microscopy: an introduction to TEM, SEM and AEM, Springer Verlag, 2007
Voraussetzungen / BesonderesNo mandatory prerequisites. Please consider the prior attendance to EM Basic lectures (551- 1618-00V; 227-0390-00L; 327-0703-00L) as suggested prerequisite.
376-0221-00LMethods and Concepts in Human Systems Neuroscience and Motor Control Belegung eingeschränkt - Details anzeigen
Maximale Teilnehmerzahl: 18
W3 KP3PN. Wenderoth
KurzbeschreibungThis course provides hands-on experience with measurement and analysis methods relevant for Humans Systems Neuroscience and Motor control (nerve/brain stimulation, EMG, EEG, psycho-physical paradigms etc). Students read scientific material, set up experiments, perform measurements in the lab, analyse data, apply statistics and write short reports or essays.
LernzielThis course will prepare students for experimental work as it is typically done during the master thesis. The goal is to gain hands-on experience with measurement and analysis methods relevant for Humans Systems Neuroscience and Motor control (ifor example peripheral nerve stimulation, electrical and magnetic brain stimulation, EMG, EEG, psycho-physical paradigms etc). Students will learn how to perform small scientific projects in this area. Students will work individually or in small groups and solve scientific problems which require them to perform measurements in human participants, extract relevant readouts from the data, apply appropriate statistics and interpret the results. They will also be required to write small essays and reports and they will get feedback on their writing throughout the course.
Voraussetzungen / BesonderesStudents are required to have successfully completed the course "Neural control of movement and motor learning" and to have basic knowledge of applied statistics. Self-study material about applied statistics will be available at the beginning of the course and statistical knowledge will be tested (central element) in the second course week. Passing this test is a requirement for continuing the course. Students will have to solve scientific problems, requiring them to independently study scientific material, apply statistics and report their results in the form of written reports and essays. Assessments will be made on the basis of the completed theoretical and practical work that will be performed either in small groups or individually.
376-0815-00LWriting your Master's Thesis: Natural Sciences and Engineering C1-C2 Belegung eingeschränkt - Details anzeigen
Findet dieses Semester nicht statt.
Your course regristration is only valid with a simultaneous online registration at the language center (www.sprachenzentrum.uzh.ch).

Number of participants limited to 15 (3 courses are available).

Attention: Registration is only possible from 12.9. (from 11.30h) - 15.9.2016
W2 KP2VS. Milligan
KurzbeschreibungWe'll prepare you to produce your MSc thesis. You'll learn how to structure your thesis, write scientific English, and manage your writing efficiently. You'll receive detailed feedback on work in progress.
LernzielBy the end of the course students are able to plan, draft, and edit academic English papers and theses; structure and write clear texts in a style which is acceptable to their academic discourse community; manage the writing process efficiently; select formal vocabulary and use it in a generally accurate and correct manner; choose and use generally suitable grammatical structures, punctuation, and orthographic conventions, assess their own effectiveness as writers of academic English, and identify areas in which further development is needed.
InhaltThe course covers the writing context; the writing process; structuring sentences, paragraphs, longer sections (such as introduction, methods, results, and discussion), and whole texts; presenting and integrating non-textual elements such as graphs and tables; and editing and correcting drafts and proofs. Each lesson comprises a mixture of elements, including specialist input, individual tasks, pairwork, and groupwork. Active participation is expected.
376-1177-00LHuman Factors IW2 KP2VM. Menozzi Jäckli, R. Huang, M. Siegrist
KurzbeschreibungEvery day humans interact with various systems. Strategies of interaction, individual needs, physical & mental abilities, and system properties are important factors in controlling the quality and performance in interaction processes. In the lecture, factors are investigated by basic scientific approaches. Discussed topics are important for optimizing people's satisfaction & overall performance.
LernzielThe goal of the lecture is to empower students in better understanding the applied theories, principles, and methods in various applications. Students are expected to learn about how to enable an efficient and qualitatively high standing interaction between human and the environment, considering costs, benefits, health, and safety as well. Thus, an ergonomic design and evaluation process of products, tasks, and environments may be promoted in different disciplines. The goal is achieved in addressing a broad variety of topics and embedding the discussion in macroscopic factors such as the behavior of consumers and objectives of economy.
Inhalt- Physiological, physical, and cognitive factors in sensation and perception
- Body spaces and functional anthropometry, Digital Human Models
- Experimental techniques in assessing human performance and well-being
- Human factors and ergonomics in system designs, product development and innovation
- Human information processing and biological cybernetics
- Interaction among consumers, environments, behavior, and tasks
Literatur- Gavriel Salvendy, Handbook of Human Factors and Ergonomics, 4th edition (2012), is available on NEBIS as electronic version and for free to ETH students
- Further textbooks are introduced in the lecture
- Brouchures, checklists, key articles etc. are uploaded in ILIAS
376-1179-00LApplications of Cybernetics in ErgonomicsW1 KP1UM. Menozzi Jäckli, Y.‑Y. Hedinger Huang, R. Huang
KurzbeschreibungCybernetics systems have been studied and applied in various research fields, such as applications in the ergonomics domain. Research interests include the man-machine interaction (MMI) topic which involving the performance in multi-model interactions, quantification in gestalt principles in product development; or the information processing matter.
LernzielTo learn and practice cybernetics principles in interface designs and product development.
Inhalt- Fitt's law applied in manipulation tasks
- Hick-Hyman law applied in design of the driver assistance systems - Vigilance applied in quality inspection
- Accommodation/vergence crosslink function
- Cross-link models in neurobiology- the ocular motor control system
- Human performance in optimization of production lines
LiteraturGavriel Salvendy, Handbook of Human Factors and Ergonomics, 4th edition (2012)
376-1414-00LCurrent Topics in Brain Research (HS)W1 KP1.5KM. E. Schwab, F. Helmchen, S. Jessberger, I. Mansuy, weitere Dozierende
KurzbeschreibungEs werden verschiedene wissenschaftliche Gäste aus dem In-und Ausland eingeladen, die Ihre aktuellen Forschungsdaten präsentieren und diskutieren.
LernzielFörderung des Austauschs von wissenschaftlichen Erkenntnissen und Daten sowie der Kommunikation und Zusammenarbeit unter den Forschenden.
Für Studierende: Kritische Auseinandersetzung mit der aktuellen Forschung.
Studierende, welche den Kreditpunkt für dieses Kolloqium erhalten möchten, wählen einen Vortrag aus und schreiben einen kritischen Aufsatz über die vorgestellte Forschungsarbeit.
InhaltVerschiedene wissenschaftliche Gäste aus den Bereichen Molekulares Bewusstsein, Neurochemie, Neuromorphologie und Neurophysiologie berichten über ihre neuesten wissenschaftlichen Erkenntnisse.
Skriptkein Skript
Literaturkeine
376-1504-00LPhysical Human Robot Interaction (pHRI) Belegung eingeschränkt - Details anzeigen
Number of participants limited to 26.
W4 KP2V + 2UR. Gassert, O. Lambercy
KurzbeschreibungThis course focuses on the emerging, interdisciplinary field of physical human-robot interaction, bringing together themes from robotics, real-time control, human factors, haptics, virtual environments, interaction design and other fields to enable the development of human-oriented robotic systems.
LernzielThe objective of this course is to give an introduction to the fundamentals of physical human robot interaction, through lectures on the underlying theoretical/mechatronics aspects and application fields, in combination with a hands-on lab tutorial. The course will guide students through the design and evaluation process of such systems.

By the end of this course, you should understand the critical elements in human-robot interactions - both in terms of engineering and human factors - and use these to evaluate and de- sign safe and efficient assistive and rehabilitative robotic systems. Specifically, you should be able to:

1) identify critical human factors in physical human-robot interaction and use these to derive design requirements;
2) compare and select mechatronic components that optimally fulfill the defined design requirements;
3) derive a model of the device dynamics to guide and optimize the selection and integration of selected components
into a functional system;
4) design control hardware and software and implement and
test human-interactive control strategies on the physical
setup;
5) characterize and optimize such systems using both engineering and psychophysical evaluation metrics;
6) investigate and optimize one aspect of the physical setup and convey and defend the gained insights in a technical presentation.
InhaltThis course provides an introduction to fundamental aspects of physical human-robot interaction. After an overview of human haptic, visual and auditory sensing, neurophysiology and psychophysics, principles of human-robot interaction systems (kinematics, mechanical transmissions, robot sensors and actuators used in these systems) will be introduced. Throughout the course, students will gain knowledge of interaction control strategies including impedance/admittance and force control, haptic rendering basics and issues in device design for humans such as transparency and stability analysis, safety hardware and procedures. The course is organized into lectures that aim to bring students up to speed with the basics of these systems, readings on classical and current topics in physical human-robot interaction, laboratory sessions and lab visits.
Students will attend periodic laboratory sessions where they will implement the theoretical aspects learned during the lectures. Here the salient features of haptic device design will be identified and theoretical aspects will be implemented in a haptic system based on the haptic paddle (Link), by creating simple dynamic haptic virtual environments and understanding the performance limitations and causes of instabilities (direct/virtual coupling, friction, damping, time delays, sampling rate, sensor quantization, etc.) during rendering of different mechanical properties.
SkriptWill be distributed through the document repository before the lectures.
http://www.relab.ethz.ch/education/courses/phri.html
LiteraturAbbott, J. and Okamura, A. (2005). Effects of position quantization and sampling rate on virtual-wall passivity. Robotics, IEEE Transactions on, 21(5):952 - 964.
Adams, R. and Hannaford, B. (1999). Stable haptic interaction with virtual environments. Robotics and Automation, IEEE Transactions on, 15(3):465 -474.
Buerger, S. and Hogan, N. (2007). Complementary stability and loop shaping for improved human ndash;robot interaction. Robotics, IEEE Transactions on, 23(2):232 -244.
Burdea, G. and Brooks, F. (1996). Force and touch feedback for virtual reality. John Wiley & Sons New York NY.
Colgate, J. and Brown, J. (1994). Factors affecting the z-width of a haptic display. In Robotics and Automation, 1994. Proceedings., 1994 IEEE International Conference on, pages 3205 -3210 vol.4.
Diolaiti, N., Niemeyer, G., Barbagli, F., and Salisbury, J. (2006). Stability of haptic rendering: Discretization, quantization, time delay, and coulomb effects. Robotics, IEEE Transactions on, 22(2):256 -268.
Gillespie, R. and Cutkosky, M. (1996). Stable user-specific haptic rendering of the virtual wall. In Proceedings of the ASME International Mechanical Engineering Congress and Exhibition, volume 58, pages 397-406.
Hannaford, B. and Ryu, J.-H. (2002). Time-domain passivity control of haptic interfaces. Robotics and Automation, IEEE Transactions on, 18(1):1 -10.
Hashtrudi-Zaad, K. and Salcudean, S. (2001). Analysis of control architectures for teleoperation systems with impedance/admittance master and slave manipulators. The International Journal of Robotics Research, 20(6):419.
Hayward, V. and Astley, O. (1996). Performance measures for haptic interfaces. In ROBOTICS RESEARCH-INTERNATIONAL SYMPOSIUM-, volume 7, pages 195-206. Citeseer.
Hayward, V. and Maclean, K. (2007). Do it yourself haptics: part i. Robotics Automation Magazine, IEEE, 14(4):88 -104.
Leskovsky, P., Harders, M., and Szeekely, G. (2006). Assessing the fidelity of haptically rendered deformable objects. In Haptic Interfaces for Virtual Environment and Teleoperator Systems, 2006 14th Symposium on, pages 19 - 25.
MacLean, K. and Hayward, V. (2008). Do it yourself haptics: Part ii [tutorial]. Robotics Automation Magazine, IEEE, 15(1):104 -119.
Mahvash, M. and Hayward, V. (2003). Passivity-based high-fidelity haptic rendering of contact. In Robotics and Automation, 2003. Proceedings. ICRA '03. IEEE International Conference on, volume 3, pages 3722 - 3728 vol.3.
Mehling, J., Colgate, J., and Peshkin, M. (2005). Increasing the impedance range of a haptic display by adding electrical damping. In Eurohaptics Conference, 2005 and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems, 2005. World Haptics 2005. First Joint, pages 257 - 262.
Okamura, A., Richard, C., and Cutkosky, M. (2002). Feeling is believing: Using a force-feedback joystick to teach dynamic systems. JOURNAL OF ENGINEERING EDUCATION-WASHINGTON-, 91(3):345-350.
O'Malley, M. and Goldfarb, M. (2004). The effect of virtual surface stiffness on the haptic perception of detail. Mechatronics, IEEE/ASME Transactions on, 9(2):448 -454.
Richard, C. and Cutkosky, M. (2000). The effects of real and computer generated friction on human performance in a targeting task. In Proceedings of the ASME Dynamic Systems and Control Division, volume 69, page 2.
Salisbury, K., Conti, F., and Barbagli, F. (2004). Haptic rendering: Introductory concepts. Computer Graphics and Applications, IEEE, 24(2):24-32.
Weir, D., Colgate, J., and Peshkin, M. (2008). Measuring and increasing z-width with active electrical damping. In Haptic interfaces for virtual environment and teleoperator systems, 2008. haptics 2008. symposium on, pages 169 -175.
Yasrebi, N. and Constantinescu, D. (2008). Extending the z-width of a haptic device using acceleration feedback. Haptics: Perception, Devices and Scenarios, pages 157-162.
Voraussetzungen / BesonderesNotice:
The registration is limited to 26 students
There are 4 credit points for this lecture.
The lecture will be held in English.
The students are expected to have basic control knowledge from previous classes.
http://www.relab.ethz.ch/education/courses/phri.html
551-0317-00LImmunology I Information W3 KP2VA. Oxenius, M. Kopf
KurzbeschreibungEinführung in strukturelle und funktionelle Eigenschaften des Immunsystems.
Grundlegendes Verständnis der Mechanismen und der Regulation einer Immunantwort.
LernzielEinführung in strukturelle und funktionelle Eigenschaften des Immunsystems.
Grundlegendes Verständnis der Mechanismen und der Regulation einer Immunantwort.
Inhalt- Einleitung und historischer Hintergrund
- Angeborene und adaptive Immunantwort, Zellen und Organe des Immunsystems
- B Zellen und Antikörper
- Generation von Diversität
- Antigen-Präsentation und Histoinkompatibilitätsantigene (MHC)
- Thymus und T Zellselektion
- Autoimmunität
- Zytotoxische T Zellen und NK Zellen
- Th1 und Th2 Zellen, regulatorische T Zellen
- Allergien
- Hypersensitivititäten
- Impfungen und immun-therapeutische Interventionen
SkriptDie Studenten haben elekronischen Zugriff auf die Vorlesungsunterlagen. Der Link ist unter "Lernmaterialien" zu finden.
Literatur- Kuby, Immunology, 7th edition, Freemen + Co., New York, 2009
Voraussetzungen / BesonderesImmunology I (WS) und Immunology II (SS) werden in einer Sessionsprüfung im Anschluss an Immunology II als eine Lerneinheit geprüft.
551-0319-00LCellular Biochemistry (Part I) Information W3 KP2VU. Kutay, R. I. Enchev, B. Kornmann, M. Peter, I. Zemp, weitere Dozierende
KurzbeschreibungConcepts and molecular mechanisms underlying the biochemistry of the cell, providing advanced insights into structure, function and regulation of individual cell components. Particular emphasis will be put on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes such as intracellular transport, cell division & growth, and cell migration.
LernzielThe full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterisation of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry.
The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain the integration of different molecules and signaling pathways into complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, cell division and cell growth. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer.
InhaltStructural and functional details of individual cell components, regulation of their interactions, and various aspects of the regulation and compartmentalisation of biochemical processes.
Topics include: biophysical and electrical properties of membranes; viral membranes; structural and functional insights into intracellular transport and targeting; vesicular trafficking and phagocytosis; post-transcriptional regulation of gene expression.
SkriptScripts and additional material will be provided during the semester. Please contact Dr. Alicia Smith for assistance with the learning materials. (alicia.smith@bc.biol.ethz.ch)
LiteraturRecommended supplementary literature (review articles and selected primary literature) will be provided during the course.
Voraussetzungen / BesonderesTo attend this course the students must have a solid basic knowledge in chemistry, biochemistry and general biology. The course will be taught in English.
551-1145-00LViral and non-Viral Vectors for Human Gene-Therapy - from Pathogens to Safe Medical Applications
Der Kurs muss direkt an der UZH belegt werden.
UZH Modulkürzel: BIO708

Beachten Sie die Einschreibungstermine an der UZH: http://www.uzh.ch/studies/application/mobilitaet.html
W2 KP3VUni-Dozierende
KurzbeschreibungBasic aspects of virology, the viral mechanisms for transfer of genetic material into cells, different vector-systems and target cells, animal models, specific applications for inborn diseases of the immune system and of metabolism, adverse effects, and new developments of vector systems will be taught.
LernzielKnowledge of important viral and non-viral vector systems.
Knowledge of application in human diseases.
Knowledge of limiting factors.
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