Rudolf Aebersold: Katalogdaten im Frühjahrssemester 2019

NameHerr Prof. Dr. Rudolf Aebersold
LehrgebietSystembiologie
E-Mailaebersold@imsb.biol.ethz.ch
DepartementBiologie
BeziehungOrdentlicher Professor

NummerTitelECTSUmfangDozierende
551-0002-00LAllgemeine Biologie II Belegung eingeschränkt - Details anzeigen 4 KP4GU. Sauer, R. Aebersold, W. Gruissem
KurzbeschreibungGrundlagen der
Biochemie (Makromoleküle, Membranen, Zellstrukturen, Stoffwechsel)
Molekulargenetik (Genexpression und Regulation, vom Gen zum Protein)
Physiologie höherer Pflanzen (Struktur, Wachstum, Entwicklung, Nährstoffe, Transport und Reproduktion)
LernzielVerständnis grundlegender Konzepte molekularer Biologie und Physiologie.
InhaltZellluläre Funktionen auf der Ebenen von Molekülen und Strukturen.
Molekulare Vorgänge in der Prozessierung vom Gen zum Protein.
Pflanzenphysiologie.

Die folgenden Campbell Kapitel werden behandelt:

Woche 1-5: Prof. Sauer
5 Biological macromolecules and lipids
7 Cell structure and function
8 Cell membranes
10 Respiration: introduction to metabolism
10 Cell respiration
11 Photosynthetic processes

Woche 6-9: Prof. Aebersold
16 Nucleic acids and inheritance
17 Expression of genes
18 Control of gene expression
19 DNA Technology

Woche 9-13: Prof. Gruissem
35 Plant Structure and Growth
36 Transport in vascular plants
37 Plant nutrition
38 Reproduction of flowering plants
39 Plants signal and behavior
SkriptKein Skript
LiteraturCampbell, Reece et al: "Biologie" (10th global edition); Pearson 2015.
551-0003-AALGeneral Biology I+II
Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben.

Alle andere Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen.
7 KP13RU. Sauer, R. Aebersold, W. Gruissem, O. Y. Martin, A. Widmer
KurzbeschreibungGeneral Biology I: Organismic biology to teach the basic principles of classical and molecular genetics, evolutionary biology and phylogeny.

General Biology II: Molecular biology approach to teach the basic principles of biochemistry, cell biology, cgenetics, evolutionary biology and form and function of vacular plants.
LernzielGeneral Biology I: The understanding of basic principles of biology (inheritance, evolution and phylogeny) and an overview of the diversity of life.

General Biology II: The understanding basic concepts of biology: the hierarchy of the structural levels of biological organisation, with particular emphasis on the cell and its molecular functions, the fundamentals of metabolism and molecular genetics, as well as form and function of vascular plants.
InhaltGeneral Biology I:
General Biology I focuses on the organismal biology aspects of genetics, evolution and diversity of life in the Campbell chapters 12-34.

Week 1-7 by Alex Widmer, Chapters 12-25
12 Cell biology Mitosis
13 Genetics Sexual life cycles and meiosis
14 Genetics Mendelian genetics
15 Genetics Linkage and chromosomes
20 Genetics Evolution of genomes
21 Evolution How evolution works
22 Evolution Phylogentic reconstructions
23 Evolution Microevolution
24 Evolution Species and speciation
25 Evolution Macroevolution

Week 8-14 by Oliver Martin, Chapters 26-34
26 Diversity of Life Introdution to viruses
27 Diversity of Life Prokaryotes
28 Diversity of Life Origin & evolution of eukaryotes
29 Diversity of Life Nonvascular&seedless vascular plants
30 Diversity of Life Seed plants
31 Diversity of Life Introduction to fungi
32 Diversity of Life Overview of animal diversity
33 Diversity of Life Introduction to invertebrates
34 Diversity of Life Origin & evolution of vertebrates


General Biology II: The structure and function of biomacromolecules; basics of metabolism; tour of the cell; membrane structure and function; basic energetics of cellular processes; respiration, photosynthesis; cell cycle, from gene to protein; structure and growth of vascular plants, resource acquisition and transport, soil and plant nutrition.

Specifically the following Campbell chapters will be covered:
3 Biochemistry Chemistry of water
4 Biochemistry Carbon: the basis of molecular diversity
5 Biochemistry Biological macromolecules and lipids
7 Cell biology Cell structure and function
8 Cell biology Cell membranes
10 Cell biology Respiration: introduction to metabolism
10 Cell biology Cell respiration
11 Cell biology Photosynthetic processes
16 Genetics Nucleic acids and inheritance
17 Genetics Expression of genes
18 Genetics Control of gene expression
19 Genetics DNA Technology
35 Plant structure&function Plant Structure and Growth
36 Plant structure&function Transport in vascular plants
37 Plant structure&function Plant nutrition
38 Plant structure&function Reproduction of flowering plants
39 Plant structure&function Plants signal and behavior
SkriptNo script
LiteraturCampbell et al. (2015) Biology - A Global Approach. 10th Edition (Global Edition)
Voraussetzungen / BesonderesBasic general and organic chemistry


This is a virtual self-study lecture for non-German speakers of the "Allgemeine Biology I (551-0001-00L) and "Allgemeine Biology II (551-0002-00L) lectures. The exam will be written jointly with the participants of this lecture.
551-0224-00LAdvanced Proteomics Belegung eingeschränkt - Details anzeigen
Für Masterstudierende ab 2. Semester, Doktorierende und Postdoktorierende
4 KP6GR. Aebersold, L. Gillet, M. Gstaiger, A. Leitner, P. Pedrioli
KurzbeschreibungZiel dieses Kurses ist es, etablierte und neue Technologien der Protein- und Proteome-Analyse kennenzulernen in Bezug auf ihre Anwendung in Biologie, Biotechnologie und Medizin.
Format: Einführung durch Dozent mit anschliessender Diskussion, unterstützt durch Literaturarbeit und Übungen.
LernzielIm Kurs werden sowohl die bereits etablierten als auch die neuesten derzeit entstehenden Technologien und Methoden in der Protein- und Proteomanlayse diskutiert im Hinblick auf ihre Anwendung in der Biologie, Biotechnologie, Medizin und Systembiologie.
InhaltBlock course teaching current methods for the acquisition and processing of proteomic datasets.
Voraussetzungen / BesonderesNumber of people: Not exceeding 30.
Students from ETHZ, Uni Zurich and University of Basel
Non-ETH students must register at ETH Zurich as special students http://www.rektorat.ethz.ch/students/admission/auditors/index_EN
551-0324-00LSystems Biology Information 6 KP4VR. Aebersold, B. Christen, M. Claassen, U. Sauer
KurzbeschreibungIntroduction to experimental and computational methods of systems biology. By using baker’s yeast as a thread through the series, we focus on global methods for analysis of and interference with biological functions. Illustrative applications to other organisms will highlight medical and biotechnological aspects.
Lernziel- obtain an overview of global analytical methods
- obtain an overview of computational methods in systems biology
- understand the concepts of systems biology
InhaltOverview of global analytical methods (e.g. DNA arrays, proteomics, metabolomics, fluxes etc), global interference methods (siRNA, mutant libraries, synthetic lethality etc.) and imaging methods. Introduction to mass spectrometry and proteomics. Concepts of metabolism in microbes and higher cells. Systems biology of developmental processes. Concepts of mathematical modeling and applications of computational systems biology.
Skriptno script
LiteraturThe course is not taught by a particular book, but some books are suggested for further reading:

- Systems biology in Practice by Klipp, Herwig, Kowald, Wierling und Lehrach. Wiley-VCH 2005