Renato Zenobi: Catalogue data in Autumn Semester 2022

Award: The Golden Owl
Name Prof. Dr. Renato Zenobi
FieldAnalytische Chemie
Address
Lab. für Organische Chemie
ETH Zürich, HCI E 329
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
SWITZERLAND
Telephone+41 44 632 43 76
Fax+41 44 632 12 92
E-mailrenato.zenobi@org.chem.ethz.ch
DepartmentChemistry and Applied Biosciences
RelationshipFull Professor

NumberTitleECTSHoursLecturers
529-0041-00LModern Mass Spectrometry, Hyphenated Methods, and Chemometrics6 credits3GR. Zenobi, B. Hattendorf, P. Sinués Martinez-Lozano
AbstractModern mass spectrometry, hyphenated analytical methods, speciation, chemometrics.
ObjectiveComprehensive knowledge about the analytical methods introduced in this course and their practical applications.
ContentHyphenation of separation with identification methods such as GC-MS, LC-MS, GC-IR, LC-IR, LC-NMR etc.; importance of speciation.
Modern mass spectrometry: time-of-flight, orbitrap and ion cyclotron resonance mass spectrometry, ICP-MS. Soft ionization methods, desorption methods, spray methods. Mass spectrometry imaging.
Use of statistical and computer-assisted methods for processing analytical data (chemometrics).
Lecture notesLecture notes will be made available online.
LiteratureInformation about relevant literature will be available in the lecture & in the lecture notes.
Prerequisites / NoticeExercises are an integral part of the lecture.
Prerequisites:
529-0051-00 "Analytische Chemie I (3. Semester)"
529-0058-00 "Analytische Chemie II (4. Semester)"
(or equivalent)
Fostered competenciesFostered competencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Decision-makingnot assessed
Media and Digital Technologiesnot assessed
Problem-solvingassessed
Project Managementnot assessed
Social CompetenciesCommunicationnot assessed
Cooperation and Teamworknot assessed
Customer Orientationnot assessed
Leadership and Responsibilitynot assessed
Self-presentation and Social Influence not assessed
Sensitivity to Diversitynot assessed
Negotiationnot assessed
Personal CompetenciesAdaptability and Flexibilitynot assessed
Creative Thinkingassessed
Critical Thinkingassessed
Integrity and Work Ethicsnot assessed
Self-awareness and Self-reflection not assessed
Self-direction and Self-management not assessed
529-0043-01LAnalytical Strategy6 credits3GR. Zenobi, K. Eyer, S. Giannoukos, D. Günther
AbstractProblem-oriented development of analytical strategies and solutions.
ObjectiveAbility to create solutions for particular analytical problems.
ContentIndividual development of strategies for the optimal application of chemical, biochemical, and physico-chemical methods in analytical chemistry solving predefined problems. Experts from industry and administration present particular problems in their field of activity.
Principles of sampling.
Design and application of microanalytical systems.
Lecture notesCopies of problem sets and solutions will be distributed free fo charge
Prerequisites / NoticePrerequisites:
529-0051-00 "Analytical Chemistry I (3. Semester)"
529-0058-00 "Analytical Chemistry II (4. Semester)"
(or equivalent)
Fostered competenciesFostered competencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Decision-makingassessed
Media and Digital Technologiesnot assessed
Problem-solvingassessed
Project Managementnot assessed
Social CompetenciesCommunicationassessed
Cooperation and Teamworkassessed
Customer Orientationnot assessed
Leadership and Responsibilitynot assessed
Self-presentation and Social Influence not assessed
Sensitivity to Diversitynot assessed
Negotiationnot assessed
Personal CompetenciesAdaptability and Flexibilitynot assessed
Creative Thinkingassessed
Critical Thinkingassessed
Integrity and Work Ethicsnot assessed
Self-awareness and Self-reflection not assessed
Self-direction and Self-management not assessed
529-0051-AALAnalytical Chemistry I
Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement.

Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit.

The underlying lecture (529-0051-00L) is offered in autumn semester but only in German.
3 credits6RD. Günther, R. Zenobi
AbstractIntroduction into the most important spectroscopical methods and their applications to gain structural information.
ObjectiveKnowledge about the necessary theoretical background of spectroscopical methods and their practical applications
ContentApplication oriented basics of organic and inorganic instrumental analysis and of the empirical employment of structure elucidation methods:
Mass spectrometry: Ionization methods, mass separation, isotope signals, rules of fragmentation, rearrangements.
NMR spectroscopy: Experimental basics, chemical shift, spin-spin coupling.
IR spectroscopy: Revisiting topics like harmonic oscillator, normal vibrations, coupled oscillating systems (in accordance to the basics of the related lecture in physical chemistry); sample preparation, acquisition techniques, law of Lambert and Beer, interpretation of IR spectra; Raman spectroscopy.
UV/VIS spectroscopy: Basics, interpretation of electron spectra. Circular dichroism (CD) und optical rotation dispersion (ORD).
Atomic absorption, emission, and X-ray fluorescence spectroscopy: Basics, sample preparation.
Lecture notesScript will be provided for the production price
Literature- R. Kellner, J.-M. Mermet, M. Otto, H. M. Widmer (Eds.) Analytical Chemistry, Wiley-VCH, Weinheim, 1998;
- D. A. Skoog und J. J. Leary, Instrumentelle Analytik, Springer, Heidelberg, 1996;
- M. Hesse, H. Meier, B. Zeeh, Spektroskopische Methoden in der organischen Chemie, 5. überarbeitete Auflage, Thieme, Stuttgart, 1995
- E. Pretsch, P. Bühlmann, C. Affolter, M. Badertscher, Spektroskopische Daten zur Strukturaufklärung organischer verbindungen, 4. Auflage, Springer, Berlin/Heidelberg, 2001-
Kläntschi N., Lienemann P., Richner P., Vonmont H: Elementanalytik. Instrumenteller Nachweis und Bestimmung von Elementen und deren Verbindungen. Spektrum Analytik, 1996, Hardcover, 339 S., ISBN 3-86025-134-1.
Prerequisites / NoticeExcercises are integrated in the lectures. In addition, attendance in the lecture 529-0289-00 "Instrumental analysis of organic compounts" (4th semester) is recommended.
529-0051-00LAnalytical Chemistry I3 credits3GD. Günther, M.‑O. Ebert, G. Schwarz, R. Zenobi
AbstractIntroduction into the most important spectroscopical methods and their applications to gain structural information.
ObjectiveKnowledge about the necessary theoretical background of spectroscopical methods and their practical applications
ContentApplication oriented basics of organic and inorganic instrumental analysis and of the empirical employment of structure elucidation methods:
Mass spectrometry: Ionization methods, mass separation, isotope signals, rules of fragmentation, rearrangements.
NMR spectroscopy: Experimental basics, chemical shift, spin-spin coupling.
IR spectroscopy: Revisiting topics like harmonic oscillator, normal vibrations, coupled oscillating systems (in accordance to the basics of the related lecture in physical chemistry); sample preparation, acquisition techniques, law of Lambert and Beer, interpretation of IR spectra; Raman spectroscopy.
UV/VIS spectroscopy: Basics, interpretation of electron spectra. Circular dichroism (CD) und optical rotation dispersion (ORD).
Atomic absorption, emission, and X-ray fluorescence spectroscopy: Basics, sample preparation.
Lecture notesScript will be for the production price
Literature- R. Kellner, J.-M. Mermet, M. Otto, H. M. Widmer (Eds.) Analytical Chemistry, Wiley-VCH, Weinheim, 1998;
- D. A. Skoog und J. J. Leary, Instrumentelle Analytik, Springer, Heidelberg, 1996;
- M. Hesse, H. Meier, B. Zeeh, Spektroskopische Methoden in der organischen Chemie, 5. überarbeitete Auflage, Thieme, Stuttgart, 1995
- E. Pretsch, P. Bühlmann, C. Affolter, M. Badertscher, Spektroskopische Daten zur Strukturaufklärung organischer verbindungen, 4. Auflage, Springer, Berlin/Heidelberg, 2001-
Kläntschi N., Lienemann P., Richner P., Vonmont H: Elementanalytik. Instrumenteller Nachweis und Bestimmung von Elementen und deren Verbindungen. Spektrum Analytik, 1996, Hardcover, 339 S., ISBN 3-86025-134-1.
Prerequisites / NoticeExcercises are integrated in the lectures. In addition, attendance in the lecture 529-0289-00 "Instrumental analysis of organic compounts" (4th semester) is recommended.
529-0058-AALAnalytical Chemistry II
Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement.

Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit.

This course does not offer a lecture of its own but it is linked to the course 529-0058-00L.
3 credits6RD. Günther, M.‑O. Ebert, G. Schwarz, R. Zenobi
AbstractEnhanced knowledge about the elemental analysis and spectrocopical techniques with close relation to practical applications. This course is based on the knowledge from analytical chemistry I. Separation methods are included.
ObjectiveUse and applications of the elemental analysis and spectroscopical knowledge to solve relevant analytical problems.
ContentCombined application of spectroscopic methods for structure determination, and practical application of element analysis. More complex NMR methods: recording techniques, application of exchange phenomena, double resonance, spin-lattice relaxation, nuclear Overhauser effect, applications of experimental 2d and multipulse NMR spectroscopy, shift reagents. Application of chromatographic and electrophoretic separation methods: basics, working technique, quality assessment of a separation method, van-Deemter equation, gas chromatography, liquid chromatography (HPLC, ion chromatography, gel permeation, packing materials, gradient elution, retention index), electrophoresis, electroosmotic flow, zone electrophoresis, capillary electrophoresis, isoelectrical focussing, electrochromatography, 2d gel electrophoresis, SDS-PAGE, field flow fractionation, enhanced knowledge in atomic absorption spectroscopy, atomic emission spectroscopy, X-ray fluorescence spectroscopy, ICP-OES, ICP-MS.
Literaturegeneral: R. Kellner, J.-M. Mermet, M. Otto, H. M. Widmer (Eds.) Analytical Chemistry, Wiley-VCH, Weinheim, 1998;
XRF: R. Schramm, X-Ray Fluorescence Analysis: Practical and Easy, Fluxana, Kleve, 2012;
ICP-MS: R. Thomas, Practical Guide to ICP-MS - A Tutorial for beginners, 3rd Edition, CRC Press, Taylor & Francis Group, Boca Raton, 2013 (especially: chapters 1-15, 19 and 21).
Separation methods: S. Ahuja (Ed.), Chromatography and Separation Science, Volume 4 of series "Separation Science and Technology", Elsevier Academic Press, San Diego, 2003.
K. Robards, P. R. Haddad, and P. E. Jackson, Principle and Practise of Modern Chromatographic Methods, Academic Press, London, 1994.
F. Foret, L. Krivankova, and P. Bocek, Capillary Zone Electrophoresis, VCH, Weinheim (1993)
Prerequisites / NoticeNone.
529-0280-00LAnalytical Chemistry Seminar0 credits1KR. Zenobi
AbstractAnalytical Chemistry Seminar
ObjectivePresentation and discussion of current research topics in analytical chemistry
ContentPresentation and discussion of current research topics in analytical chemistry
529-0290-00LOrganic Chemistry (Seminar) Restricted registration - show details 0 credits2SE. M. Carreira, J. W. Bode, H. Wennemers, R. Zenobi
Abstract
Objective
529-0299-00LOrganic Chemistry0 credits1.5KJ. W. Bode, E. M. Carreira, P. Chen, H. Wennemers, R. Zenobi
Abstract
Objective